About Us

Alpha-1 Targeted Detection Program

The Alpha-1 Antitrypsin Genetics Laboratory at GeneAidyx is an international reference laboratory for Alpha-1 Antitrypsin levels, phenotype, and genotype analysis. The laboratory has partnered with the Alpha-1 Foundation and Grifols to help the Alpha community and their families by providing free, quick, convenient, and confidential genetic testing for Alpha-1 Antitrypsin Deficiency.

The GeneAidyx laboratory is a CLIA certified lab (ID 10D2083230), holding additional certificates in California (ID COS00800549), Florida (ID 800027407), Maryland (ID 1671), New York (PFI 8552), and Pennsylvania (ID 034248) for immunology and genetic testing. GeneAidyx participates in a proficiency testing program through the College of American Pathologists. The laboratory staff at GeneAidyx are HIPAA certified and sign confidentiality agreements with the company on an annual basis.

Currently, three Alpha-1 detection programs are utilizing the services of the GeneAidyx Alpha-1 Antitrypsin Genetics Laboratory. Through these programs, testing is provided confidentially and free of charge to healthcare providers and their patients.

National Targeted Alpha-1 Detection Program – Grifols, Inc. is supporting a nationwide targeted detection program for Alpha-1. Test kits and laboratory processing are provided to healthcare providers and patients free of charge. The test is administered through doctors’ offices using a finger stick test available from Grifols, Inc. Your test result is communicated directly to your ordering physician to ensure accurate interpretation and HIPAA compliance. For healthcare providers wishing to obtain a Grifols Alpha-1 test kit, please call toll free 800-562-7222 or visit https://orderalphakits.myalphakit.com/geneaidyx_form.aspx

Alpha-1 Coded Testing (ACT) Trial –The Medical University of South Carolina (MUSC) is currently conducting a research study sponsored by the Alpha-1 Foundation which evaluates perceived risks and benefits of genetic testing. The Alpha-1 Coded Testing (ACT) Trial offers free and confidential finger-stick testing for Alpha-1 Antitrypsin Deficiency. The test can be completed at home and results are mailed to the participant’s home. Anyone can request to be tested. Participants or the participant’s guardian must submit a short pre- and post-test questionnaire. If you wish to participate in ACT, please call toll free 877-886-2383 or send an email to: alphaone@musc.edu.

Testing for Alpha-1 through all these programs is simple, quick, and highly accurate. The finger stick collection system utilized requires only a small prick to the finger and a few drops of blood on the test card. The sample is sent to the lab for processing and results are typically ready in 10 days.

The Alpha-1 Antitrypsin Genetics Laboratory has been the reference laboratory to analyze the clinical study samples for 3 of the 4 available IV drugs in the market. Over the past decade, we have tested over 400,000 subjects and have identified nearly 5,600 subjects with severe Alpha-1 Antitrypsin Deficiency and over 30,000 subjects with mild to moderate deficiency.

State of Florida Alpha-1 Detection Program is now closed – The State of Florida Department of Health and Human Services and the Alpha-1 Foundation sponsored this detection program from 1999 to August 2017. The program focused on targeted population screening, patient and physician education, and treatment programs for AAT Deficiency. This program was free to Florida residents and is administered through healthcare providers’ offices using a finger stick test available from the Alpha-1 Foundation. Your test result was communicated directly to your ordering physician to ensure accurate interpretation and HIPAA compliance.